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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUAK1
All Species:
18.18
Human Site:
S516
Identified Species:
30.77
UniProt:
O60285
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60285
NP_055655.1
661
74305
S516
P
A
R
V
T
S
H
S
L
S
C
R
R
K
G
Chimpanzee
Pan troglodytes
XP_001161041
661
74289
S516
P
A
R
V
T
S
H
S
L
S
C
R
R
K
G
Rhesus Macaque
Macaca mulatta
XP_001098986
667
74748
S522
P
A
R
V
T
S
H
S
L
S
C
R
R
K
G
Dog
Lupus familis
XP_538417
666
74288
G521
P
A
R
G
P
V
L
G
L
S
C
R
R
K
G
Cat
Felis silvestris
Mouse
Mus musculus
Q641K5
658
73643
S517
P
A
R
G
T
S
H
S
L
S
C
R
R
K
G
Rat
Rattus norvegicus
Q66HE5
630
69934
S495
G
D
P
M
E
Q
K
S
P
Q
A
S
G
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508265
661
73136
S516
P
T
R
L
G
S
P
S
L
A
Y
R
R
K
G
Chicken
Gallus gallus
Q9IA88
798
88848
C508
E
G
T
S
S
D
S
C
L
T
S
S
S
N
D
Frog
Xenopus laevis
NP_001088596
570
64876
K435
A
G
R
K
G
I
L
K
R
N
G
K
F
S
S
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
S838
S
L
S
R
F
H
T
S
A
Y
E
Q
L
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649991
1427
153426
P1139
H
V
I
T
I
Q
R
P
P
T
Q
H
A
Y
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
Q682
P
L
N
S
T
A
V
Q
G
H
R
T
A
T
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P92958
512
58671
V376
G
H
W
I
P
A
H
V
D
H
Y
G
L
G
A
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
P495
P
A
A
S
K
I
S
P
L
V
T
K
K
S
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.9
91.7
N.A.
90.9
55.6
N.A.
84.2
26.1
48.5
23.5
N.A.
24.3
N.A.
22.4
N.A.
Protein Similarity:
100
99.8
98
94.4
N.A.
93.8
68
N.A.
88
42.8
61.4
36.2
N.A.
33.6
N.A.
35.8
N.A.
P-Site Identity:
100
100
100
66.6
N.A.
93.3
6.6
N.A.
60
6.6
6.6
6.6
N.A.
6.6
N.A.
20
N.A.
P-Site Similarity:
100
100
100
66.6
N.A.
93.3
20
N.A.
73.3
20
20
13.3
N.A.
13.3
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.1
26.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
49.3
46.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
43
8
0
0
15
0
0
8
8
8
0
15
0
15
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
36
0
0
0
0
% C
% Asp:
0
8
0
0
0
8
0
0
8
0
0
0
0
0
8
% D
% Glu:
8
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
15
15
0
15
15
0
0
8
8
0
8
8
8
8
58
% G
% His:
8
8
0
0
0
8
36
0
0
15
0
8
0
0
0
% H
% Ile:
0
0
8
8
8
15
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
8
8
0
8
8
0
0
0
15
8
43
8
% K
% Leu:
0
15
0
8
0
0
15
0
58
0
0
0
15
0
8
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
8
0
0
0
8
0
% N
% Pro:
58
0
8
0
15
0
8
15
15
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
15
0
8
0
8
8
8
0
0
0
% Q
% Arg:
0
0
50
8
0
0
8
0
8
0
8
43
43
8
0
% R
% Ser:
8
0
8
22
8
36
15
50
0
36
8
15
8
15
8
% S
% Thr:
0
8
8
8
36
0
8
0
0
15
8
8
0
15
0
% T
% Val:
0
8
0
22
0
8
8
8
0
8
0
0
0
0
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
15
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _